Experts at Ohio Poison Centers say they’re seeing an increase in children taking excessive amounts of diphenhydramine—more commonly known as Benadryl. The so‑called “ Benadryl challenge,” circulating on social media, encourages high doses to trigger hallucinations or a recreational “high.” Dr. Shan Yin, Medical Director of the Cincinnati Drug and Poison Information Center (DPIC), explains the serious dangers.